Collaborative research between The Clinical and Practice Research Group at the School of Pharmacy, Queen’s University Belfast and the Northern Health and Social Care Trust has been ongoing for some 30 years. The collaboration has involved a broad range of areas within clinical pharmacy, including the development of time series analysis models to assist in antimicrobial stewardship, integrated medicines management systems, new approaches to discharge planning (including recent work on telephone follow-up) and developing algorithms for risk of rehospitalisation. Ongoing work includes the impact of GP practice-based pharmacists on medicines optimisation and the development of pharmacist led outpatient medicines management clinics. International PhD students have performed a key role in delivering the research programmes over the years and have formed a platform for ongoing international collaborations.